Sample Sizes for Clinical Trials

Sample Sizes for Clinical Trials, Second Edition, is a practical book that assists researchers in their estimation of the sample size for clinical trials. Throughout the book, there are detailed worked examples to illustrate how to do both the calculations and how to present them to colleagues or in protocols. The book also highlights some of the pitfalls in calculations as well as the key steps that lead to the final sample size calculation.
The book is primarily aimed at researchers and practitioners of clinical trials and biostatistics and could be used to teach a course on sample size calculations. The importance of a sample size calculation when designing a clinical trial is highlighted in the book. It enables readers to quickly find an appropriate sample size formula, with an associated worked example, complemented by tables to assist in the calculations.
Steven A. Julious is a professor of medical statistics at the University of Sheffield and has over 30 years of applied research experience. His research interests, in both an academic and pharmaceutical setting, include clinical trials, clinical trial design and the development of new methodologies related to clinical trials.